It will be easy to do:
Get the pinout of the socket and the pinout of the desired eprom, for example 64k or more.
In the pins of the eprom not located in the board put a binary switch like this:
http://es.farnell.com/c-k-components/rte1601n43/switch-rotary-hexadecimal-100ma/dp/1648978

Simply an idea:
Why not the rom in the cartidge to make it plug and play?